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Microfluidics International Corporation - PureNano Continuous Crystallizer - MRT-CR5

As leading pharmaceutical companies continue to explore the benefits of continuous manufacturing and bottom-up nanoparticle creation, Microfluidics' PureNano Continuous Crystallizer is being used to create stabile inhalable formulations, improve the bioavailability of antibiotics and target delivery of novel cancer treatments, among other possibilities.

PureNano is a platform technology with several innovative applications:

  • Continuous crystallization
  • Efficient nanoencapsulation
  • Chemical reactions
  • Process intensification

Microfluidics has successfully demonstrated these applications on the lab scale (up to 0.5 liters/min).

Technical Specifications

Flow-rate range 100 to 500 ml/min (water) depending on operating pressure, product characteristics and chamber selection
Operating Pressure Range 138 to 1,380 bar (2,000 to 20,000 psi)
Sample Size 50 ml to continuous
Minimum product hold upvolume 42 ml
Dimensions: (H x W x D) 58 x 119 x 66 cm (23” x 47” x 26”) approximately, depending on options
Weight 204 kg (450 lb.), approximately
Available models

Standard features:

  • Up to 2,000 psi (135 bar)
  • Flow rates to 2 lpm

Available options:

  • Coling coil
  • Sanitary flush diaphragm pressure transducer with microprocessor-based, digital-display indicator
  • Autoclavable air motor
  • 400ml manual pressure feed reservoir
  • Pressurized feed tank
  • Selection of homogenizer modules for normal or high viscosity processing

Standard features:

  • Up to 5,000 psi (345 bar)
  • Flow rates to 950 ml/min

Available options:

  • Cooling coil
  • Sanitary flush diaphragm pressure transducer with microprocessor-based, digital display indicator
  • Autoclavable air motor
  • 400ml manual pressure feed reservoir
  • Pressurized feed tank
  • Selection of homogenizer modules for normal or high viscosity processing
  • Large scale production of nanoparticles with high purity and efficiency at low operational cost
  • Synthesis of fine chemicals through single or multiphase reactions
  • Process Intensification
  • Biopharmaceutical and Biotechnology
  • Chemical
  • Cosmetics & Personal Care
  • Education & Academics
  • Food & Beverage
  • Medical
  • Paper & Wood
  • Pharmaceutical
  • Polymers, Plastics and Rubbers
  • Powders & Pigments / Coating
  • Malaysia
  • Singapore
Microfluidics International CorporationMicrofluidics International Corporation, the manufacturer of Microfluidizer® high shear fluid processors, is a leader in the design and production of laboratory and commercial processing equipment used in the production of micro- and nano-scale materials for pharmaceutical, biotech, chemical and diverse industries. Microfluidizer® technology enables some of the world’s top companies to create superior products, develop intellectual property, improve process efficiency and capitalize on new revenue streams. We set the standard for nanoemulsion and nanoparticle applications. Since 2011, Microfluidics has been a member of the IDEX Corporation family of companies. IDEX is a global leader in highly engineered systems and components. We are part of the IDEX Material Processing Technologies group, a collection of companies that manufacture a range of technologically superior processing equipment for a wide variety of materials. All process equipment, solutions and support provided by this group are optimized to meet the unique needs of each and every customer.
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