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Malvern - Particle Metrology System - Archimedes

Archimedes is a new, highly innovative instrument which uses the technique of resonant mass measurement to detect and accurately count particles in the size range 50nm - 5µm, and reliably measure their buoyant mass, dry mass and size.

Particularly useful for the characterization of protein aggregates in formulation or buffer, Archimedes is also able to distinguish between proteinaceous material and contaminants such as silicone oil by means of comparing their relative resonant frequencies and buoyant masses.

Parameters measured:

  • Particle number
  • Particle size.
  • Particle buoyant mass.
  • Particle dry mass.
  • Particle density.
  • Particle surface area.
  • Sample volume.
  • Sample concentration (particles/mL).
  • Sample density.

For applications about Malvern Archimedes, click here

DKSH is the exclusive distributor in Cambodia, Indonesia, Laos, Malaysia, Myanmar, Philippines, Singapore, Taiwan, Thailand and Vietnam.

Technical Specifications

Dimensions 610 mm × 585 mm × 305 mm
Weight 23.6 kg
Particle Size Measurement- Measurement Range 500 nm - 5 µm
Particle Size Measurement- Accuracy Better than +/- 1% on NIST traceable latex standards.
Particle Size Measurement- Precision/Repeatability Better than +/- 1% on NIST traceable latex standards.
Particle Size Measurement- Resolution Better than +/- 20nm at 1µm, polystyrene beads in H₂O
Particle Buoyant Mass Measurement- Lower Detection Limit 450 ag
Particle Buoyant Mass Measurement- Accuracy Better than +/- 3% on NIST traceable latex standards.
Particle Buoyant Mass Measurement- Precision/Repeatability Better than +/- 3% on NIST traceable latex standards.
Particle Counting / Sample Concentration Measurement- Measurement Range 10⁴ particles / mL – 10⁹ particles / mL.
Particle Counting / Sample Concentration Measurement- Accuracy Better than +/- 10% on NIST traceable latex standards
Particle Counting / Sample Concentration Measurement- Precision/Repeatability Better than +/- 5% on NIST traceable latex standards.
Measurement Principle: Resonant Mass Measurement- Drawn sample volume 100 µL
Measurement Principle: Resonant Mass Measurement- Measured Sample Volume Range 10 nL - 10 µL
Measurement Principle: Resonant Mass Measurement- Sample Viscosity Range < 1 cP - 100 cP
Measurement Principle: Resonant Mass Measurement- Accuracy in fluid density < 0.002 g / cc for densities in range 0.8 g / cc – 1.2 g / cc.
Measurement Principle: Resonant Mass Measurement- Light source 685 nm, 35 mW laser
Operating environment- Power 110 V or 220 V
Operating environment- Temperature 18°C - 25°C
Humidity 35% - 80%
  • Ideally positioned for biopharmaceutical manufacturers and developers.

  • Unique and accurate particle counting capability in the size range 50 nm - 5 µm.

  • Exquisite sensitivity: measurement of particle mass to 350 ag.

  • Highly accurate particle size measurement from 50 nm to 5 µm.

  • Excellent size resolution, < 20 nm at 1 µm diameter.

  • Low sample consumption: only 100 µL

  • Differentiation between negatively buoyant and positively buoyant particles.

  • Capable of measuring high concentration samples (to 109 particles / mL) and high viscosity samples (to 100 cP).

  • Fast, NIST-traceable calibration.

  • Highly reproducible results.

  • Intuitive and flexible ParticleLab software.

  • Aerospace
  • Agriculture
  • Automotive
  • Biopharmaceutical and Biotechnology
  • Chemical
  • Construction
  • Cosmetics & Personal Care
  • Defense
  • Die & Mould
  • Education & Academics
  • Electronics
  • Energy
  • Environmental
  • Food & Beverage
  • Luxury
  • Machinery & Manufacturing
  • Medical
  • Mining & Minerals
  • Oil & Gas
  • Optical
  • Paper & Wood
  • Pharmaceutical
  • Polymers, Plastics and Rubbers
  • Powders & Pigments / Coating
  • Railway
  • Semiconductor, Solar & Electronics
  • Service
  • Textile
  • Wholesale & Retail

Malvern Archimedes - Particle Count using Resonant Mass Measurement

Malvern Instruments' Archimedes is a new, highly innovative instrument which uses the technique of resonant mass measurement to detect and accurately count particles (particle concentration) in the size range 50nm - 5µm, and reliably measure their buoyant mass, dry mass and size. Particularly useful for the detection and protein characterization, including protein aggregates in formulation or buffer,
Archimedes is also able to distinguish between proteinaceous material and contaminants such as silicone oil by means of comparing their relative resonant frequencies and buoyant masses. For more information, please click here

  • Cambodia
  • Indonesia
  • Laos
  • Malaysia
  • Myanmar
  • Philippines
  • Singapore
  • Taiwan
  • Thailand
  • Vietnam
Malvern Instruments LimitedMalvern systems are used to measure particle size, particle shape, zeta potential, protein charge, molecular weight, mass, size and conformation, microcalorimetry, rheological properties and for chemical identification, advancing the understanding of dispersed systems across many different industries and applications.
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