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The double color DRX2 analyzer offers the simultaneous measurement of two different species of probes on the same biochip electrode. Each sensor spot carries two nanolever sequences, one with a red tag, and one with a green. The instrument tracks the movement and position of the different nanolevers separately and simultaneously. This technology offers novel methods of investigation including same-spot controls, dual binding modelling, ideal for bispecifics and Proof of Action experiments with two nanolevers to play with, using one nanolever for capture and the second for detection.
|Limit of detection||10 fM|
|Dissociation constant||50 fM – 1 mM|
|Association rate constant||1E3 – 1E8 /Ms|
|Dissociation rate constant||1E-6 – 1E0 /s|
|Hydrodynamic diameter accuracy||0.1 nm|
|Temperature||8° – 75°C (chip), 10° – 40°C (autosampler)|