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Advance with Confidence

The Zetasizer Pro is a robust and versatile system for the measurement of particle and molecular size and electrophoretic mobility and zeta potential of nanoparticles. It enables size measurements to be performed up to three times quicker, compared to previous models, accelerating sample throughput and freeing up operator and system time for other tasks.

Even novice users will produce the highest-quality measurements, thanks to the intuitive interface and the deep learning empowered data quality advice system that highlights issues and provides advice on how to overcome them.


The Zetasizer Pro is a robust and versatile solution for routine laboratory measurements of molecular size, particle size, electrophoretic mobility and zeta potential. Size measurements can now be performed more than twice as quickly, compared to previous models, accelerating sample throughput and freeing up operator and system time for other tasks.


ZS Xplorer software is designed to simplify and automate even complex analysis, allowing challenging measurements to be completed without expert knowledge. Its unique samplecentric workflow delivers the ultimate in usability and flexibility,  meaning it’s faster and easier than ever to get from sample input to result output.


A common challenge with light scattering is dust contamination – this can now be
intelligently identified and filtered from the data. It’s also immediately apparent if
results aren’t quite as expected and need a little more attention. Integrated deeplearning empowered data quality guidance offers instant feedback, flagging any queries and providing actionable advice on how to improve lower quality data.

Technical specifications

Detector Avalanche photodiode
Temperature and control range 0°C - 120°C
Temperature accuracy 0.1°C at 25°C, 0.2°C at 0°C, 0.5°C at 90°C, 2.5°C at 120°C
Dimensions (W, D, H) 322 mm x 565 mm x 245 mm
Weight 19 kg
Power AC 100-240 V, 50-60 Hz, 4.0 A
Measurement principle:
Particle size and molecular size
Dynamic light scattering (Non- Invasive Back-Scatter - NIBS)
Dynamic light scattering (13°, 173°)
Measurement principle:
Zeta potential
Mixed-mode measurement, phase analysis light scattering (M3-PALS)

Key features

  • Dynamic Light Scattering (DLS) measures particle and molecule size, from below 1 nm to 10 μm
  • Electrophoretic Light Scattering (ELS) measures the zeta potential of particles and molecules, indicating sample stability and/or propensity to aggregate
  • Sample-centric ZS Xplorer software enables flexible, guided use, and provides assistance as required
  • The deep-learning empowered Data Quality System assists users in understanding which of their size data might be poor, and why. This intelligent neural network system also suggests how to improve results, helping less-experienced users generate excellent quality data
  • Optical filter wheel offers a fluorescence filter and both vertical and horizontal polarizers for analytical flexibility
  • Adaptive Correlation enables the software to determine optimum measurement duration, and identifies data associated with transient artefacts. Reliable and repeatable data is produced over twice as quickly, providing a truly representative view of the sample
  • NIBS (Non-Invasive Back-Scatter) technology maximizes the dynamic range, providing the highest sensitivity for even the most concentrated samples
  • M3-PALS with Constant Current Mode measures electrophoretic mobility and zeta potential in high conductivity media – reducing errors that can be associated with electrode polarization at higher ion concentrations

Zetasizer Pro and Zetasizer Ultra: Countdown to Launch!

  • Aerospace
  • Agriculture
  • Biopharmaceutical and Biotechnology
  • Chemical
  • Cosmetics & Personal Care
  • Die & Mould
  • Education & Academics
  • Electronics
  • Environmental
  • Food & Beverage
  • Machinery & Manufacturing
  • Medical
  • Mining & Minerals
  • Oil & Gas
  • Optical
  • Paper & Wood
  • Pharmaceutical
  • Polymers, Plastics and Rubbers
  • Powders & Pigments / Coating
  • Semiconductor, Solar & Electronics
  • Textile
Malvern PanalyticalMalvern Panalytical was formed by the merger of Malvern Instruments Limited and PANalytical B.V. on 1st January 2017, has headquarters in both Almelo (the Netherlands), and in Malvern (UK), and employs over 2,000 people worldwide. The combined entity is a strong player and innovator in the materials characterization market and will leverage the strengths of the individual companies in their end markets, ranging from building materials to pharmaceuticals and from metals and mining to nanomaterials.
[Zetasizer pro, light scattering characterization, particle size analysis, zeta potential analysis, molecule size analysis]