SARTORIUS - Flexsafe^® Pro Mixer

Easy to Install, Ergonomically Designed
The Flexsafe^® Pro Mixer has been designed from the ground up for ease of operation.

• With a single-operator installation that can be completed in less than 10 minutes, changeovers become faster and more efficient.
• The drive-unit guidance across the mixing process supports single-person operation while reducing the risk of operator error.
• A cubical design with front access to sensors and tubing help prevent handling errors while improving ergonomics and ease of use.

Low-Shear Mixing
The Flexsafe^® Pro Mixer is designed to reduce or eliminate the risk of shear degradation.

• The levitating impeller makes this single-use mixer ideal for a range of applications, including viral inactivation and formulation of sensitive drug substances and products.
• Its unique design eliminates shear effects that can impact product quality while avoiding the generation of aggregates and particles that can cause fouling of filters.

High-Performance and Rapid Mixing
The Flexsafe^® Pro Mixer enables faster dissolution when mixing powders into liquids, saving time and expense.

• A strong vertical vortex, combined with the baffle effect of the cubical design, allows instant downward movement and efficient dissolution of floating powders.
• Its high-torque impeller is particularly effective and efficient in mixing high-concentration or viscous powders.
• The faster powder dissolution resulting from the Flexsafe® Pro Mixer's unique design saves time during buffer and media preparations and results in a more efficient process overall.

Integrated and Intelligent Process Monitoring
The Flexsafe^® Pro Mixer is an intelligent single-use mixer designed to control critical mixing parameters in cGMP production.

• Inline controls that monitor pH, conductivity, and temperature help meet PAT and cGMP requirements while decreasing operator time, and the pre-assembled single-use pH probe eliminates any risk of contamination from reusable probes.
• The Palletank, the Flexsafe^® Pro Mixer stainless-steel mixing tank, is available with weighing functions and heat exchange jacket for integrated control of volume and temperature.
• The Flexsafe^® Pro Mixer drive unit features an automated control of the mixing parameters by reading the real impeller speed, offering mixing recipes, and managing passwords.

Flexibility of Use
The Flexsafe^® Pro Mixer offers a unique single-use technology accommodating a wide range of mixing steps in both upstream and downstream processes.

• A single-drive unit appropriate for managing a range of volumes and functions offers flexibility across the biomanufacturing process.
• By accommodating the need for both low-shear and rapid-mixing applications, the Flexsafe® Pro Mixer supports mixing steps from media formulation and buffer preparations, downstream process steps to final formulation. 
• The Flexsafe^® Pro Mixer is a reliable option for the development of monoclonal antibodies, vaccines, and biosimilars.