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OpenSPR is the world’s only benchtop surface plasmon resonance (SPR) instrument. It provides high quality, label-free interaction analysis for a fraction of the cost of existing solutions. Our unique nano-structured sensor surface uses localized SPR (LSPR) to deliver repeatable, highly sensitive kinetic data.

OpenSPR-XT is built with our cutting-edge and affordable nanotechnology biosensor platform. It has been seamlessly integrated with our robust autosampler system to allow for fully automated, 24/7 operation.

Compatible with:

  • Proteins
  • Lipids
  • Carbohydrates
  • Antibodies
  • Nucleic acids
  • Small molecules
  • Cells
  • Viruses
  • Nanoparticles & more

Applications:

  • Kinetics/affinity characterization
  • Competition assays
  • Target identification
  • Epitope mapping
  • Screening
  • Yes/No binding
  • Concentration

 

Available models

Performance
Association rate (kon)
1×103–1×107 1/M*s
Dissociation rate (koff)
0.1–1×10-5 1/s
Affinity range (KD)
mM-pM
Hardware
Number of channels
2
Flow rate
5–200 μL/min
Injection
Semi-Automated
Injection volume
5–100 μL
Autosampler
Optional upgrade to OpenSPR-XT
Temperature range
4°C-40°C (max 10°C < ambient)
Temperature precision
+/- 0.25°C
Buffer switching
3 ports available, automated switching
Instrument size
46 x 34 x 21 cm
Weight
42 lbs
File output
CSV, Tracedrawer

Obtain publication-quality binding kinetics & affinity data on your benchtop.

Performance
Association rate (kon)
1×103–1×107 1/M*s
Dissociation rate (koff)
0.1–1×10-5 1/s
Affinity range (KD)
mM-pM
Hardware
Number of channels
2
Flow rate
5–200 μL/min
Injection
Automated
Injection volume
5–100 μL
Sample capacity
2x 96 well plates, 2/10 mL vials
Sample temperature
Cooled from 20°C-4°C
Unattended run time
24 hours
Temperature range
4°C-40°C (max 10°C < ambient)
Temperature precision
+/- 0.25°C
Buffer switching
3 ports available, automated switching
Instrument size
78 x 55 x 53 cm
File output
CSV, Tracedrawer

Maximize your productivity with fully automated, 24/7 operation of our benchtop SPR.

OpenSPR for biotechnology

Get started on your experiments in a matter of hours.

OpenSPR is user-friendly and has versatile applicability. In smaller companies, the OpenSPR allows researchers to finish off their full experimental workflows at a low cost. In larger companies, the OpenSPR is easily integrated alongside their other assays.

OpenSPR is ideal for:

  • Lead Optimization
  • Quality control
  • Drug discovery
  • Validation
  • Feasibility

OpenSPR for academia

Our mission is to improve human life by helping scientists succeed. By using innovative nanotechnology, we reduce the cost and complexity of SPR instrumentation and make it accessible to every researcher. Having OpenSPR in your own lab will eliminate the expensive costs and inconvenient travelling associated with using a shared instrument in a core facility.

Nicoya

Nicoya is a Canadian biotechnology company dedicated to improving human life by helping scientists succeed. Established in 2012, Nicoya was founded by Ryan Denomme in his relentless pursuit to use nanotechnology to increase the affordability and ease of use of scientific instruments. In less than 3 years, Nicoya has grown rapidly from 14 to 70+ employees who have extensive experience working at the forefront of nanotechnology and biotechnology sectors. Nicoya develops innovative and accessible biosensor technology for in-depth characterization of biomolecular interactions.

[Nicoya, OpenSPR, OpenSPR Instrument]