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Archimedes is a new, highly innovative instrument which uses the technique of resonant mass measurement to detect and accurately count particles in the size range 50nm - 5µm, and reliably measure their buoyant mass, dry mass and size.
Particularly useful for the characterization of protein aggregates in formulation or buffer, Archimedes is also able to distinguish between proteinaceous material and contaminants such as silicone oil by means of comparing their relative resonant frequencies and buoyant masses.
Parameters measured:
For applications about Malvern Archimedes, click here
DKSH is the exclusive distributor in Cambodia, Indonesia, Laos, Malaysia, Myanmar, Philippines, Singapore, Taiwan, Thailand and Vietnam.
| Dimensions | 610 mm × 585 mm × 305 mm |
|---|---|
| Weight | 23.6 kg |
| Particle Size Measurement- Measurement Range | 500 nm - 5 µm |
| Particle Size Measurement- Accuracy | Better than +/- 1% on NIST traceable latex standards. |
| Particle Size Measurement- Precision/Repeatability | Better than +/- 1% on NIST traceable latex standards. |
| Particle Size Measurement- Resolution | Better than +/- 20nm at 1µm, polystyrene beads in H₂O |
| Particle Buoyant Mass Measurement- Lower Detection Limit | 450 ag |
| Particle Buoyant Mass Measurement- Accuracy | Better than +/- 3% on NIST traceable latex standards. |
| Particle Buoyant Mass Measurement- Precision/Repeatability | Better than +/- 3% on NIST traceable latex standards. |
| Particle Counting / Sample Concentration Measurement- Measurement Range | 10⁴ particles / mL – 10⁹ particles / mL. |
| Particle Counting / Sample Concentration Measurement- Accuracy | Better than +/- 10% on NIST traceable latex standards |
| Particle Counting / Sample Concentration Measurement- Precision/Repeatability | Better than +/- 5% on NIST traceable latex standards. |
| Measurement Principle: Resonant Mass Measurement- Drawn sample volume | 100 µL |
| Measurement Principle: Resonant Mass Measurement- Measured Sample Volume Range | 10 nL - 10 µL |
| Measurement Principle: Resonant Mass Measurement- Sample Viscosity Range | < 1 cP - 100 cP |
| Measurement Principle: Resonant Mass Measurement- Accuracy in fluid density | < 0.002 g / cc for densities in range 0.8 g / cc – 1.2 g / cc. |
| Measurement Principle: Resonant Mass Measurement- Light source | 685 nm, 35 mW laser |
| Operating environment- Power | 110 V or 220 V |
| Operating environment- Temperature | 18°C - 25°C |
| Humidity | 35% - 80% |
Ideally positioned for biopharmaceutical manufacturers and developers.
Unique and accurate particle counting capability in the size range 50 nm - 5 µm.
Exquisite sensitivity: measurement of particle mass to 350 ag.
Highly accurate particle size measurement from 50 nm to 5 µm.
Excellent size resolution, < 20 nm at 1 µm diameter.
Low sample consumption: only 100 µL
Differentiation between negatively buoyant and positively buoyant particles.
Capable of measuring high concentration samples (to 109 particles / mL) and high viscosity samples (to 100 cP).
Fast, NIST-traceable calibration.
Highly reproducible results.
Intuitive and flexible ParticleLab software.
Malvern Instruments' Archimedes is a new, highly innovative instrument which uses the technique of resonant mass measurement to detect and accurately count particles (particle concentration) in the size range 50nm - 5µm, and reliably measure their buoyant mass, dry mass and size. Particularly useful for the detection and protein characterization, including protein aggregates in formulation or buffer,
Archimedes is also able to distinguish between proteinaceous material and contaminants such as silicone oil by means of comparing their relative resonant frequencies and buoyant masses. For more information, please click here
Malvern Panalytical was formed by the merger of Malvern Instruments Limited and PANalytical B.V. on 1st January 2017, has headquarters in both Almelo (the Netherlands), and in Malvern (UK), and employs over 2,000 people worldwide. The combined entity is a strong player and innovator in the materials characterization market and will leverage the strengths of the individual companies in their end markets, ranging from building materials to pharmaceuticals and from metals and mining to nanomaterials.
