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Zetasizer Advance is the successor to the highly successful and market-leading Zetasizer Nano.

Each of the three models in the Zetasizer Advance Range offers particle size, particle charge (zeta potential) and molecular weight analysis. In addition, each benefits from advances including Adaptive Correlation, M3-PALS zeta potential analysis, constant current zeta mode and our deep learning-based data quality advice system.

Each of the three models is available as a Blue Label or Red Label variant:

  • Choose Blue Label for routine sample investigation such as metallic colloids, metal oxides and pigments
  • Choose Red Label for more challenging sample types, such as proteins, surfactant solutions and low solid content samples

All Zetasizer Advance systems offer on-site upgradeability with minimal downtime. Should your needs change, your Zetasizer can adapt to new challenges.

Technical Specifications

Zetasizer Ultra Zetasizer Pro Zetasizer Lab
Classic 90° DLS V V
Non-Invasive Back Scatter DLS (NIBS) V V
Multi-Angle Dynamic Light Scattering (MADLS) V
Measurement type
Zeta potential V V V
Molecular weight* V V V
Particle concentration / titer Red label only

*instrument capable - software capability to be released soon

Available models

Zetasizer Ultra - Malvern Panalytical

World’s most advanced light scattering system

The new Zetasizer Ultra is our most advanced system for the measurement of particle and molecular size, particle charge and particle concentration, and represents the most intelligent and flexible instrument in the Zetasizer Advance range.

Our flagship model enjoys all the benefits afforded by ZS Xplorer software, in terms of ease of use, analysis speed and data confidence, and also offers two unique measurement capabilities: Multi-Angle Dynamic Light Scattering (MADLS®) and particle concentration*, to offer even greater insight into your samples.

High performance, versatile and robust

The new Zetasizer Pro is your go-to instrument to measure a wide range of sample types and concentrations. It offers wide dynamic concentration capability and high sensitivity due to the Non-Invasive Back Scatter (NIBS) optical design. Measurement of particle size, molecular size, electrophoretic mobility, zeta potential and molecular weight can all be performed with ease.

The Adaptive Correlation feature enhances sample throughput by reducing measurement duration and providing greater sample knowledge. The deep learning-based data quality system gives you the confidence to know your data is the best it can be. 

The optical filter wheel allows measurement of fluorescent samples without impacting overall instrument sensitivity.


Entry-level particle size and zeta potential analyzer with enhanced capabilities

Our entry-level Zetasizer does not compromise on features. The Zetasizer Lab incorporates Adaptive Correlation, M3-PALS and constant current zeta mode. The Zetasizer Lab also ships with ZS Xplorer, easy-to-use analytical software. ZS Xplorer offers instant feedback on data quality, and guidance on how to improve your results.


Advance with Confidence: Malvern Panalytical’s new Zetasizer Pro and Zetasizer Ultra


Journal of Electronic Materials | 2023 June 27 | Read Article

Large-Scale Green Electrochemical Synthesis of Smart Titanium Dioxide Nanomaterials: Controlled Morphology and Rotatable Surface Ligands via Tuning Electrolyte Structures

Quan Doan Mai, Ha Anh Nguyen, Nguyen Ngoc Huyen, …, Anh-Tuan Le

Article Snippet

The shapes and sizes of the sets of TiO2 were collected using a scanning electron microscope operating under an acceleration voltage of 5 kV. The crystal phase was investigated by x-ray diffraction under voltage of 40 kV and current of 30 mA. The optical properties of e-TiO2 were studied by ultraviolet–visible (UV-Vis) absorption spectra. Chemical properties were investigated by Raman spectroscopy. Thermal properties were studied by thermogravimetric analysis (TGA). The surface properties and stability were analyzed by ζ potential measurements (Zetasizer Ultra Red Label)… More


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Malvern PanalyticalMalvern Panalytical was formed by the merger of Malvern Instruments Limited and PANalytical B.V. on 1st January 2017, has headquarters in both Almelo (the Netherlands), and in Malvern (UK), and employs over 2,000 people worldwide. The combined entity is a strong player and innovator in the materials characterization market and will leverage the strengths of the individual companies in their end markets, ranging from building materials to pharmaceuticals and from metals and mining to nanomaterials.
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