Malvern Viscosizer TD is an automated biophysical characterization tool utilizing Taylor Dispersion Analysis and providing ultra-low volume, solution-based molecular size and stability measurement capabilities, combined with Poiseuille flow for relative viscosity assessment.
Viscosizer TD offers biopharmaceutical researchers an orthogonal technique for conformational stability analysis, which is unrivaled in extending into label-free measurements in highly complex solutions, and encompasses a critical size range from small molecules through to protein-based systems.
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| Sample measurement temp. range | 4°C - 40°C |
|---|---|
| Sample storage temp. range | 4°C - 40°C |
| Minimum measurement and storage temp. | 20°C below ambient |
| Pressure range | 0 - 3000 mbar |
| Maximum throughput | 50 sample vials per run |
| Optics wavelength | 200 nm - 325 nm |
| Filter availbale | 214 nm, 254 nm, 280 nm |
| Size range | 0.2 nm - 50 nm |
| Size accuracy | Better than 5% |
| Size repeatability | Better than 2.5% |
| Size reproducibility | Better than 2.5% |
| Viscosity range | 0.9 cP - 50 cP (or mPas) |
| Viscosity accuracy | Better than 5.5% |
| Viscosity repeatability | Better than 1% |
| Viscosity reproducibility | Better than 2.5% |
| Operating temperature | 16°C - 30°C |
UV wavelength can be changed to optimize measurement sensitivity and molecular selectivity
Novel technique for biopharmaceutical researchers to assess peptide stability and peptide solubility
Using a matched sample buffer effectively renders excipients and surfactants invisible, enabling label-free characterization of target biomolecules in complex solutions
Flexible and intuitive software interface provides fully automated test schedules and data analyses for walk-away operation
UV detection for molecular sizing allows measurements at low concentration down to microgram quantities
A brief introduction to Malvern Instruments' Viscosizer 200: enabling automatic viscosity and sizing analysis of very low volume samples, allowing key developability questions to be answered in pharmaceutical and biopharmaceutical preformulation development. Click here for more information
Malvern Panalytical was formed by the merger of Malvern Instruments Limited and PANalytical B.V. on 1st January 2017, has headquarters in both Almelo (the Netherlands), and in Malvern (UK), and employs over 2,000 people worldwide. The combined entity is a strong player and innovator in the materials characterization market and will leverage the strengths of the individual companies in their end markets, ranging from building materials to pharmaceuticals and from metals and mining to nanomaterials.
