Manual PMDI wasting is a tedious time consuming task that can result in repetitive stress injuries over time. Coupled with this risk, improper manual shaking and shake-to-fire intervals in testing can vary the delivered dose from 75% to 320% of label claim per actuation. Over or under-delivery of the delivered dose during a single actuation can change the total drug concentration, introduce variability, and impact final results.
The Kinaero™ High-Throughput Fire-Down System is a solution that precisely automates shaking and actuation of up to 10 devices simultaneously, ensuring uniform dose delivery for every shot through the life of the devices.
To help our customers bring optimally-performing orally inhaled and nasal drug products to patients around the world.
Proveris Scientific Corporation delivers innovative testing platforms, laboratory services, and deep product knowledge to customers who develop, manufacture or test orally inhaled and nasal drug products (OINDPs).
Our worldwide customer base includes the top innovator and generic pharmaceutical companies, device manufacturers, CDO/CRO/CMOs, and regulatory agencies.
By understanding the critical quality attributes affecting the performance of OINDPs, and effectively controlling them from a testing and patient usability perspective, our expert team of engineers, scientists, and service professionals can help you: