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Metrohm - NIRS XDS - MasterLab Analyzer

The NIRS XDS MasterLab Analyzer enables the rapid, nondestructive analyses of solid-state dosage forms such as tablets, capsules, film-coated tablets, gel tablets and gel capsules for manufacturers in the pharmaceuticals industry. Solids in vials can also be analyzed with the NIRS XDS MasterLab Analyzer. The analysis takes place in reflection or transmission mode. The sample input proceeds via a sample slide that can be moved in x and y direction and that is designed for trays with several tablets and/or vials. Analyses of individual samples are optimized with an iris. An optionally available coarse granular sample cell for coarse granular substances extends analysis to include practically all solid forms ranging from fine powders to coarse granular materials, e.g., pellets and flakes

Technical specifications

Measuring mode Reflection and transmission
Sample interface Direct analysis
Reflection 400–2,500 nm
Transmission 800–1,650 nm
Measuring module Hot-swappable
Detectors Reflection Silicon (400–1,100 nm), lead sulfide (1,100–2,500 nm)
Transmission InGaAs (indium gallium arsenide) 800–1,650 nm
Data collection speed 2 scans/s
Data point interval 0.5 nm
Wavelength accuracy (currently recognized standard) Reflection < 0.05 nm (SRM 1920)
Transmission < 0.05 nm (Metrohm NIRS wavelength standards)
Wavelength precision 1 < 0.005 nm
Wavelength precision 2 (instrument to instrument) < 0.020 nm
Stray light < 0.1% at 2,300 nm
Photometric linearity < 1% of the measured value
Bandpass Reflection 8.75 ±0.10 nm
Transmission 9.50 ±0.10 nm
Noise (RMS): Reflection 400–700 nm < 50 micro AU
700–2,500 nm < 20 micro AU
Noise (RMS): Transmission 850–1,100 nm < 30 micro AU
1,100–1,600 nm < 20 micro AU
Weight 39.0 kg (86.0 lbs)
Dimensions (W × H × D) 380 × 346 × 559 mm (15" × 13.6" × 22")
Operating temperature range 4.5–35°C (40–95°F)
Relative humidity 10–90% RH, non-condensing

Key features

  • Reflection and transmission analyses in one instrument
  • Sample slide for xy positioning of trays with multiple tablets or vials, iris for individual samples, optional coarse granular sample cell for coarse granular substances
  • Optimal sample analysis by adapting the measuring spot to the diameter of the sample vials or tablets
  • Universal interface for quickly changing the measuring modules in just seconds
  • Network-compatible – central result and data management (client-server solution)

NIRSystems XDS Analyzers - Pharmaceutical Testing

  • Chemical
  • Cosmetics & Personal Care
  • Oil & Gas
  • Pharmaceutical
  • Polymers, Plastics and Rubbers
  • Powders & Pigments / Coating

To serve the Asia Pacific Region better, we were established in 1996 as a wholly-owned subsidiary of Metrohm AG, Switzerland. With a history that started in 1943, Metrohm AG is the world’s leading manufacturer of uncompromising quality precision instruments for chemical ion analysis and developer of tailor-made applications that help our customers safeguard their product quality, compliance with regulations, and process optimization.

Supporting the markets in Singapore and the Asia Pacific Region, are our dedicated teams of sales, service and support personnel who are all highly skilled and competent product specialists.

[Near Infrared Spectroscopy, Near Infrare, NIR, NIRS]