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The MP350 Microlyser™ Processor is an innovation in high shear processing which utilizes a hybrid approach by incorporating Microfluidics proprietary Interaction Chamber™ technology with a unique electric pumping system, to deliver the highest cell disruption yields.

From E. coli to difficult yeast cells, the MP350 Microlyser™ can provide consistent pressure across the batch cycle to maximize protein yields and ensure high product quality in cell disruption of various cells. It has the same multi-slotted fixed-geometry Interaction Chamber™ that all Microfluidics equipment possess which provides consistent shear & uniform processing for reduced batch time & lesser passes.

The scale up to production volumes with the MP350 model is seamless & cost effective once the suitable cell disruption lab and pilot batches are achieved. Enquire with us today!

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Technical Specifications

Pressure Range Up to 2068 bar (up to 30,000 PSI)
Flow Rate Range 4.0 to 4.7 lpm (1.06 to 1.24 gpm) at 2,068 bar (30,000 psi)
Feed Temperature Range 70°C (158°F)
Dimension (L x W x H) 185 x 99 x 191 cm (73” x 39” x 75")
Weight 1,800 kg (3,970 lbs.)
Electrical Requirements 50 HP (37.3 kw)
Three Phase 415V, 90A, 50 Hz
Power Requirements 50 HP (37.3 kw)
Three Phase 415V, 90A, 50 Hz
Utility Requirements

  • Cooling Water for Lube Oil Heat Exchanger: 10 lpm (2.64 gpm) Water at 5 C to 10 C

  • Cooling Water for Process Fluid Heat Exchanger: Varies as per Application

  • Compressed Air for Feed Pump: 1.70 m3/min @ 7.2 bar (60 SCFM @ 105 psi) with -37°C to – 18°C (-35°F to 0°F) dew point

  • SIP Requirement: Require saturated clean steam supply, at 130°C & 145°C temperature @ 22.6 kg/hr. @ 2.4 bar (50 lbs./hr. @ 35 psi)"

Key Features

  • Consistent shear & uniform processing for unparallel results.
  • High wear resistance with no moving parts for little or no downtime.
  • Ability to operate at pressures up to 30,000 PSI.
  • Optimize process efficiency for lysing tough yeast, bacteria & algae cells.
  • Simplified & easy to maintain for high yield cell disruption results.
  • Cleanable, drainable & sanitary pump design for biopharma standards.
  • Designed specifically for pharmaceutical and biotech markets.
  • Engineered with full cGMP compliance in mind and includes SIP capabilities.

Extended seal life for reduced operation interruptions.

Clean in Place (CIP) capabilities for the pharma market.

High-pressure seals designed for better cleanability.

Precise temperature control for reduced denaturing & increased product yields.

  • Biopharmaceutical and Biotechnology
  • Pharmaceutical

Microfluidics International Corporation, the manufacturer of Microfluidizer® high shear fluid processors, is a leader in the design and production of laboratory and commercial processing equipment used in the production of micro- and nano-scale materials for pharmaceutical, biotech, chemical and diverse industries. Microfluidizer® technology enables some of the world’s top companies to create superior products, develop intellectual property, improve process efficiency and capitalize on new revenue streams. We set the standard for nanoemulsion and nanoparticle applications.

Since 2011, Microfluidics has been a member of the IDEX Corporation family of companies. IDEX is a global leader in highly engineered systems and components. We are part of the IDEX Material Processing Technologies group, a collection of companies that manufacture a range of technologically superior processing equipment for a wide variety of materials. All process equipment, solutions and support provided by this group are optimized to meet the unique needs of each and every customer.