Introduction to MicroCal by Ruethaitip Tiratrakulvichaya August 28, 2020

Microcalorimeters for characterization of biomolecular stability and interactions.

Ruethaitip Tiratrakulvichaya, Product manager, is here to introduce you to MicroCal from Malvern PANalytical and sneak a peak to what this powerful, analytical tools can be used to enhance the study of biological systems.

MicroCal microcalorimeters are used in a wide range of applications from basic research to the discovery and development of small molecule drugs, biotherapeutics and vaccines. Our customers include pharmaceutical, biotech, academic and governmental research institutions worldwide.


Topic: Introduction to MicroCal by Ruethaitip Tiratrakulvichaya

Duration: 45 minutes

Organized by: DKSH and Malvern PANalytical

Why MicroCal? 

  • All binding parameters (affinity, stoichiometry, enthalpy and entropy) in a single experiment.
  • Quick to first results with no assay development, no labeling, no immobilization and no molecular weight limitations.
  • Sensitivity to investigate any biomolecular interaction using as little as 10µg of protein.
  • Directly measures millimolar to nanomolar affinities (KDS) (10-2 to 10-9 M).
  • Measures nanomolar to picomolar disassociation constants using competitive binding techniques (10-9 to 10-12 M).
  • Compatible with non-aqueous solvents.

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