Corning - Supplements and Reagents - Antibiotics and Antimycotics

MW = 422.4 Technical Advantage:  Can be autoclaved, unlike ampicillin Carbenicillin is a form of penicillin and is often used in place of ampicillin because it maintains stability after being autoclaved.  Like ampicillin, carbenicillin interferes with cell-wall synthesis of actively growing cells.

Complete Certificate of Analysis available for each production lot, along with full formulation information Manufactured in a facility that is FDA registered. This product is produced under high quality industry standards.

For Customers in California only: WARNING Please refer to Safety Data Sheet (SDS) Section 15 for more information regarding California Proposition 65.

Technical Advantage:  Effective against Gram-positive and - negative Bacteria, and fungi including yeast This is a combination of penicillin, streptomycin and Amphotericin formulated to contain 10,000 units/ml penicillin G, 10 mg/ml streptomycin sulfate and 25 µg/ml amphotericin B.  Penicillin acts by inhibiting bacterial cell-wall synthesis, Streptomycin inhibits prokaryote protein synthesis, and Amphotericin B interferes with fungal membrane permeability.  This combination is effective against Gram-negative and Gram-positive bacteria, fungi and yeasts.  The form provided by Mediatech is solubilized in a proprietary citrate buffer and is recommended for use in cell culture applications at 10 ml/L.

Complete Certificate of Analysis available for each production lot, along with full formulation information Manufactured in a facility that is FDA registered. This product is produced under high quality industry standards.

Technical Advantage:  Effective against Gram-positive and -negative bacteria Puromycin Dihydrochloride is a nucleoside antibiotic and protein synthesis inhibitor.  By acting as an analog of the 3'-terminal end of aminoacyl-tRNA, it prevents growth of bacteria, protozoa, algae, and mammalian cells by causing premature protein termination.  The resistance gene (puromycin acetyltransferase) gives very effective protection.  It is effective against Gram-negative and Gram-positive bacteria.

Complete Certificate of Analysis available for each production lot, along with full formulation information Manufactured in a facility that is FDA registered. This product is produced under high quality industry standards.

For Customers in California only: WARNING Please refer to Safety Data Sheet (SDS) Section 15 for more information regarding California Proposition 65.

Streptomycin is an antibiotic which acts as a protein synthesis inhibitor.  This aminoglycoside acts by binding to the 30S ribocomal subunit, preventing protein production and leading to bacterial cell death.  Streptomycin is more effective against Gram-positive bacteria than Gram-negative and is offered in a powder form.

Complete Certificate of Analysis available for each production lot, along with full formulation information Manufactured in a facility that is FDA registered. This product is produced under high quality industry standards.

250 µg/mL solubilizedThis antimycotic interferes with fungal membrane permeability by forming channels in cell membranes, causing small molecules to leak from the cell.  It is recommended for use in cell culture applications at 10 ml/L and is stable at 37ºC for 3 days.

Complete Certificate of Analysis available for each production lot, along with full formulation information Manufactured in a facility that complies with ISO 13485 certified quality system. This product is produced under high quality industry standards.

Blasticidin S HCl is produced by Streptomyces griseochromogenes and inhibits translation in both prokaryotes and eukaryotes, thus preventing the formation of peptide bonds.

Complete Certificate of Analysis available for each production lot, along with full formulation information Manufactured in a facility that is FDA registered. This product is produced under high quality industry standards.

Chloramphenicol is a common antibiotic which inhibits microbial protein synthesis by preventing peptide bond formation.  It is effective against Gram-positive and Gram-negative bacteria.

Complete Certificate of Analysis available for each production lot, along with full formulation information Manufactured in a facility that complies with ISO 13485 certified quality system. This product is produced under high quality industry standards.

Application: Recommended for use as a selection agent at 100-800 μg/mL. Biochem/physiol Actions: Mode of Action: Blocks polypeptide synthesis and inhibits elongation. For use in the selection and maintenance of prokaryotic and eukaryotic cells. Preparation Note: Purified by ion exchange chromatography.

Complete Certificate of Analysis available for each production lot, along with full formulation information Manufactured in a facility that is FDA registered. This product is produced under high quality industry standards.

For Customers in California only: WARNING Please refer to Safety Data Sheet (SDS) Section 15 for more information regarding California Proposition 65.

Technical Advantage:  Effective against Gram-positive and -negative bacteria Tetracycline Hydrochloride (HCl) is an antibiotic that inhibits protein synthesis by binding to the 30S ribosomal subunit, blocking interactions at the acceptor site on the RBA-ribosome complex.  It is a member of the tetracycline group of antibiotics, a broad-spectrum class that inhibits growth of both aerobic and anaerobic organisms through this common mechanism.  The congener tetracycline is semi-synthetically produced from chlortetracycline, a product of Staphylococcus aureofaciens.  Resistance is conferred by the TetR-Tn10 gene product that blocks cell wall permeability.  Tetracycline HCl is effective against Gram-positive and -negative bacteria and is offered in powder form.

Complete Certificate of Analysis available for each production lot, along with full formulation information Manufactured in a facility that complies with ISO 13485 certified quality system. This product is produced under high quality industry standards.

For Customers in California only: WARNING Please refer to Safety Data Sheet (SDS) Section 15 for more information regarding California Proposition 65.

Neomycin is a member of the aminoglycosides, aminoglycosidic aminocyclitols consisting of a six-membered aminocyclitol ring attached to aminosugar side chains through a glycosidic bond. Technical Advantage:  Effective against Gram-positive and -negative bacteria Neomycin, a nucleoside antibiotic and aminoglycoside, is a protein synthesis inhibitor that causes premature chain termination by acting as an analog of the 3'-terminal end of aminoacyl-tRNA.  It prevents growth of bacteria, protozoa, algae, and mammalian cells.  Organisms carrying the resistance gene puromycin acetyltransferase are effectively protected from this compound.  Neomycin is effective against Gram-negative and Gram-positive bacteria.

Complete Certificate of Analysis available for each production lot, along with full formulation information Manufactured in a facility that complies with ISO 13485 certified quality system. This product is produced under high quality industry standards.