Corning - Supplements and Reagents - Growth Factors and Cytokines

The Corning portfolio of cytokines, growth factors, and media supplementation offers a wide array of proteins that result in proliferation or differentiation of the affected cells.

• Vialed, highly purified growth factors with high biological activity
• Broad range of highly purified natural and recombinant lymphokines
• Enriched culture supplements to be reconstituted/added in the medium of your choice
• Propagate your cells under more defined serum-reduced or serum-free conditions

Growth factors are proteins that bind to receptors found on the surface of non-hematopoietic cells. Each family of growth factors affect specific cell types, e.g., nerve growth factors (NGF) affect nerve cell types, and epidermal growth factors (EGF) affect epithelial cell types.

Corning offers a range of growth factors that are derived from different species, both natural and recombinant. These growth factors have been used to promote long-term proliferation in cell culture and to induce cell differentiation in a variety of cell types under serum-free or reduced serum conditions.

The Corning portfolio of cytokines, growth factors, and media supplementation offers a wide array of proteins that result in proliferation or differentiation of the affected cells.

• Vialed, highly purified growth factors with high biological activity
• Broad range of highly purified natural and recombinant lymphokines
• Enriched culture supplements to be reconstituted/added in the medium of your choice
• Propagate your cells under more defined serum-reduced or serum-free conditions

Cytokines are a class of signaling molecules or intercellular mediators (proteins, peptides, and glycoproteins) that primarily affect cells of the immune system; however they can affect various cell types outside of the immune system. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. The effects of cytokines on cells can yield different outcomes. Some cytokines cause cell proliferation, while others may cause chemotaxis between cell types, and others can even cause cell death. Cytokines and growth factors are similar in their structure and mechanism of action. Both bind and initiate signaling pathways and many share several intracellular signaling components.

Corning offers a range of cytokines and glycoproteins that are derived from different species. These cytokines have been used to promote long-term proliferation in cell culture and to induce cell-mediated immune responses in a variety of cell types.

The Corning portfolio of cytokines, growth factors, and media supplementation offers a wide array of proteins that result in proliferation or differentiation of the affected cells.

• Vialed, highly purified growth factors with high biological activity
• Broad range of highly purified natural and recombinant lymphokines
• Enriched culture supplements to be reconstituted/added in the medium of your choice
• Propagate your cells under more defined serum-reduced or serum-free conditions

Corning offers a broad range of other media growth supplements. Some products are specific to cell type, such as SMC4 (for iPSCs) and T-Cell culture supplement (for T-cells), while other products promote proliferation in a wide variety of cell types. Reducing serum use is made easy with products such as ITS and Corning Nu-Serum™.