Dynamic Biosensors

	heliX	heliX⁺	Double-heliX	4-heliX Bundle
No. of chips, auto-exchangeable	1	5	10	20
No. of real-time signals	2	4	8	16
No. of well-plates / wells	1 / 96	1 / 384	2 / 768	4 / 1536
Fluorescence channels	One color	Two Colors	Two Colors	Two Colors
Sampling rate	1 datapoint/s	100 datapoints/s	100 datapoints/s	100 datapoints/s
Temperature	T_const.= 25°C or 37°C	[1] any constant temperature from 10° to 40°C [2] variable temperature, ramp speed up to 10°C/min	[1] any constant temperature from 10° to 40°C [2] variable temperature, ramp speed up to 10°C/min	[1] any constant temperature from 10° to 40°C [2] variable temperature, ramp speed up to 10°C/min
Measurement modes	[1] Molecular Dynamics [2] Fluor. Proximity Sens.	[1] Molecular Dynamics (molecular friction) [2] Fluorescence Proximity Sensing (FPS) [3] Fluorescence resonance energy transfer (FRET)	[1] Molecular Dynamics (molecular friction) [2] Fluorescence Proximity Sensing (FPS) [3] Fluorescence resonance energy transfer (FRET)	[1] Molecular Dynamics (molecular friction) [2] Fluorescence Proximity Sensing (FPS) [3] Fluorescence resonance energy transfer (FRET)

heliX

heliX⁺

Double-heliX

4-heliX Bundle

No. of chips,
auto-exchangeable

No. of real-time signals

No. of well-plates / wells

1 / 96

1 / 384

2 / 768

4 / 1536

Fluorescence channels

One color

Two Colors

Sampling rate

1 datapoint/s

100 datapoints/s

Temperature

T_const.= 25°C or 37°C

[1] any constant temperature from 10° to 40°C
[2] variable temperature, ramp speed up to 10°C/min

Measurement modes

[1] Molecular Dynamics
[2] Fluor. Proximity Sens.

[1] Molecular Dynamics (molecular friction)
[2] Fluorescence Proximity Sensing (FPS)
[3] Fluorescence resonance energy transfer (FRET)

Highlights

heliX^® adapter chip and sensor functionalization

Automated sensor exchange

Load up to 5 chips in one rack and switch automatically between 5 channels and 10 sensor spots.

RFID near field communication

Between instrument and chip for seamless traceability of chip status and usage history. Ideal for quality-controlled GxP environments and consistent, error-free results.

Robust microfluidics

Simplistic single-channel design, made from durable glass, withstanding highest flow rates and corrosive chemicals, disposable.

2 detection spots x 2 colors

For real-time referenced measurements of 2 interactions, or monitoring of up to 4 interactions simultaneously.