We have a wide range of offerings to cover the global fluidics market with each system having unique features to meet your system requirements. Bio-Safe™ systems are made of virgin PEEK material and offer metal-free biocompatible option for inert applications. Modular systems offer a threaded tube and a unique frit cap design. Our Iso-Bar system has an all metal design applicable for UHPLC. These column systems provide many benefits to customers looking to optimize their fluidic instruments.
Ultra-high performance liquid chromatography (UHPLC) decreases the time and costs associated with analytical separations. To consistently maintain the technology advantage, you need column hardware that ensures the speed and precision of your processes. The IsoBar column platform delivers a leak-proof, reliable, all-metal design with high strength threaded end fittings to meet critical system operating requirements.
Short length and narrow inner diameter makes Accel-X columns ideally suited for the high-speed separations commonly used in LC/MS. Near-zero-dead-volume fittings permit Accel-X columns to achieve high efficiency and excellent peak shape.
To take advantage of the high efficiency and high speed of the Accel-X LC/MS columns, it is essential to use 0.005” inner diameter capillary tubing between the injector / column and the column /detector (or LC/MS interface). This ensures minimal band broadening (sample dilution) for sharper, more efficient peaks and lower detection levels. Reducing the tubing volume (length and inner diameter) also maintains the integrity of fast gradients. Accel-X™ Columns can withstand pressures up to 15,000 psi (1,034 bar).
Modular hardware guarantees a high-pressure seal between the tubing and end fitting, as well as a proper seating of the frit. The frit is contained in a cap that slides over the column, forming a leak-free and gap-free seal. All stainless steel modular columns use our exclusive Isobore™ internal surface finish. Modular column hardware systems include the following components: one 316 stainless steel column body, two one-piece end fittings and two frit caps containing 316 stainless steel frits in a PEEK™ cap. Modular systems are available in several IDs and lengths. Modular column systems can typically operate at pressures up to 15,000 psi (1034 bar).
Bio-Safe™ columns are “biocompatible” and precision-machined from virgin PEEK™ (polyetheretherketone), a strong, inert polymer material, and are metal free for biotechnology and ion chromatography applications. PEEK columns are used when analytes are sensitive to the metals in stainless steel hardware. Proteins, peptides, and ions may have this susceptibility. PEEK is also compatible with most mobile phases used in HPLC. While THF will cause PEEK to swell, this is generally limited to PEEK capillary tubing <1.0 mm ID.
Available products of Bio-Safe™ Systems:
Our PEEK-Lined Stainless Steel (PLS) Column Hardware is designed specifically for UHPLC bio inert applications. The PLS column hardware combines the strength of our stainless steel UHPLC column (IsoBar) with the chemical inertness of PEEK polymer to ensure the integrity of biological samples by minimizing unwanted surface interactions while also allowing operation under harsh solvent or pH conditions. This hardware has been designed for demanding applications within the UHPLC realm. The PLS column is available in a variety of standard lengths to accommodate various application requirements. Each column hardware design contains removable frits in Titanium and PEEK options. For custom lengths or frit porosities please contact us for more information.