The double color DRX2 analyzer offers the simultaneous measurement of two different species of probes on the same biochip electrode. Each sensor spot carries two nanolever sequences, one with a red tag, and one with a green. The instrument tracks the movement and position of the different nanolevers separately and simultaneously. This technology offers novel methods of investigation including same-spot controls, dual binding modelling, ideal for bispecifics and Proof of Action experiments with two nanolevers to play with, using one nanolever for capture and the second for detection.
Limit of detection | 10 fM |
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Dissociation constant | 50 fM – 1 mM |
Association rate constant | 1E3 – 1E8 /Ms |
Dissociation rate constant | 1E-6 – 1E0 /s |
Hydrodynamic diameter accuracy | 0.1 nm |
Temperature | 8° – 75°C (chip), 10° – 40°C (autosampler) |